In the modern sense, Euphorbia s.l. is a large genus of ca. 2000 species characterized by its cyathium (an involucre of clustered, reduced male and female flowers). Euphorbia s.l. includes other traditionally recognized genera such as Chamaesyce, Pedilanthus, and Poinsettia (see Horn et al. 2012; Yang et al. 2012). The Florida species formerly placed in the genus Chamaesyce are now reclassified under Euphorbia subg. Chamaesyce sect. Anisophyllum subsect. Hypericifoliae. The Florida species formerly placed in the genus Poinsettia are now reclassified under Euphorbia subg. Chamaesyce sect. Poinsettia subsect. Stormieae. The former genus Pedilanthus is reclassified under Euphorbia subg. Euphorbia sect. Crepidaria. Many species have a toxic sap, and toxicity from exposure to poinsettia has been reported (D'Arcy 1974).